TMZ reports that Brown, who was in town for a Howard University Homecoming after party, allegedly began punching a man after they got into an argument outside the W Hotel around 4:30 a.m.
Law enforcement told the website that the 24-year-old singer did not appear under the influence.
Brown, who has had a string of run-ins with the law and is still on probation for violently beating ex-girlfriend Rihanna, was brought into custody.
TMZ reports the other man is “being evaluated” at a hospital. According to ABC7, another man, 35-year-old Christopher Hollosy, was also arrested.